WHO approves first vaccine to increase access in Africa

The MVA-BN vaccine, developed by Danish pharmaceutical company Bavarian Nordic, has recently received prequalification from the World Health Organization (WHO). This approval allows the vaccine to be used in adults and has already been approved in Europe and the United States. This milestone is significant in the fight against the deadly mpox virus, particularly in Africa where the outbreak has been most severe.

The WHO’s Director-General, Tedros Adhanom Ghebreyesus, emphasized the importance of this prequalification in combating the spread of the virus and saving lives. He stressed the need for urgent procurement, donations, and rollout of the vaccine to ensure equitable access in regions where it is most needed. This vaccine approval is a crucial step in the ongoing battle against infectious diseases and serves as a beacon of hope for future outbreaks.

The MVA-BN vaccine is administered in two doses, four weeks apart, in adults aged 18 and older. It boasts an estimated effectiveness of 82%, making it a promising tool in preventing the transmission of the mpox virus. While the vaccine is primarily recommended for adults, it may also be used in specific circumstances for infants, young children, pregnant women, and immunocompromised individuals.

In situations where vaccine supply is limited, WHO recommends distributing the vaccine in single doses, which still provides a significant level of protection at 76% effectiveness. This flexibility in dosing allows for strategic allocation of the vaccine to maximize its impact in high-risk populations. The prequalification of the MVA-BN vaccine will streamline procurement processes for governments and international organizations, such as Gavi and UNICEF, facilitating faster access to this life-saving intervention.

The approval of the MVA-BN vaccine represents a crucial turning point in the global fight against infectious diseases. By ensuring equitable access to vaccines and promoting widespread vaccination campaigns, we can significantly reduce the burden of illness and death caused by preventable diseases. The WHO’s endorsement of the MVA-BN vaccine underscores the importance of international cooperation in addressing public health challenges and underscores the need for continued investment in research and development of new vaccines and treatments.

The prequalification of the MVA-BN vaccine by the WHO is a testament to the tireless efforts of scientists, researchers, and healthcare professionals who have worked tirelessly to develop safe and effective vaccines. This milestone serves as a reminder of the power of vaccines to protect individuals and communities from infectious diseases and underscores the critical role of global health organizations in ensuring access to life-saving interventions.

As we navigate the ongoing challenges posed by infectious diseases, the approval of the MVA-BN vaccine offers a glimmer of hope for a brighter, healthier future. By working together to promote vaccination, we can build a more resilient and prepared global health system that is equipped to respond to emerging threats and protect the well-being of people around the world.

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